Our cardiologists modify European guidelines

heartNew guidelines for the management of acute myocardial infarction in patients with ST-segment elevation were presented during the Congress of the European Society of Cardiology 2017 held in Barcelona on 26-30 August.
The 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation were developed by a specially appointed Task Force of the European Society of Cardiology (ESC). The recommendations are based on the results of numerous research studies carried out worldwide, including three projects conducted in Poland. One of them is the randomised, placebo-controlled IMPRESSION trial analysing the impact of morphine on the pharmacokinetics and pharmacodynamics of ticagrelor in post-infarction patients, conducted at the Department of Cardiology and Internal Diseases of the Faculty of Medicine at NCU Collegium Medicum.

Results of the world’s first randomised clinical trial which demonstrated the negative effect of morphine on ticagrelor exposure and on its antithrombotic activity in patients with acute myocardial infarction – one the leading causes of death in industrialised countries – were presented in the publication: "Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial". The paper was published in the European Heart Journal (Impact Factor 20.213), one of the world-leading cardiology journals published by the European Society of Cardiology, and its findings were included in the new ESC Guidelines.